ICASSP 2006 - May 15-19, 2006 - Toulouse, France

Technical Program

Paper Detail

Paper:BIO-P2.5
Session:Bioinformatics
Time:Wednesday, May 17, 16:30 - 18:30
Presentation: Poster
Topic: Bio Imaging and Signal Processing: Bioinformatics, genomics, and proteomics
Title: DNA-RESIDUAL: A DNA COMPRESSION ALGORITHM USING FORWARD LINEAR PREDICTION
Authors: Rony Ferzli, Lina Karam, Arizona State University, United States
Abstract: This paper presents an efficient lossless DNA compression algorithm, DNA-Residual, that significantly decreases the average bit-rate required to losslessly code correlated DNA sequences. The algorithm can be divided into two parts: modeling and coding. The modeling part consists of mapping the DNA bases into a binary representation and, then, a forward linear prediction filter is used to predict the current input from the previous ones. The prediction error is then transformed into a binary error sequence that is coded using an adaptive binary arithmetic coder. Compared to state-of-the-art compressors using benchmark DNA sequences, the proposed algorithm reveals a significantly higher compression ratio whenever correlation between bases is high.



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